產品屬性：
產品名稱 | TFEB activator 1 |
規格 | 10mg、25mg、50mg、100mg |
貨號 | EY-01Y16994 |
Cas No.: 39777-61-2
別名: Curcumin analog C1
化學名: N/A
分子式: C19H18O3
分子量: 294.34
溶解度: DMSO: 125 mg/mL (424.68 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment[1].[1]. Song JX, et al. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Autophagy. 2016 Aug 2;12(8):1372-89.
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