產(chǎn)品屬性：
產(chǎn)品名稱 | αvβ1 integrin-IN-1 TFA |
規(guī)格 | 10mM*1 mL in DMSO、5 mg、10 mg、50 mg、100 mg |
貨號 | EY-01Y17129 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C28H35F3N6O8S
分子量: 672.67
溶解度: DMSO : 250 mg/mL (371.65 mM; Need ultrasonic)
儲存條件: 4°C, away from moisture
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
αvβ1 integrin-IN-1 TFA (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects[1].αvβ1 integrin-IN-1 TFA (Compound C8) significantly reduces the fibrotic markers in mouse model for liver and lung fibrosis[1].[1]. Reed NI, et al. Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective αvβ1 Integrin Inhibitors. ACS Med Chem Lett. 2016 Aug 30;7(10):902-907.
特別提醒公司產(chǎn)品僅供科研使用
