產品屬性：
產品名稱 | Nabumetone-d3 |
規格 | 1 mg |
貨號 | EY-01Y17250 |
Cas No.: 1216770-08-9
別名: N/A
化學名: N/A
分子式: C15H13D3O2
分子量: 231.3
溶解度: Chloroform: slightly soluble,Ethyl Acetate: slightly soluble
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Nabumetone-d3 is intended for use as an internal standard for the quantification of nabumetone by GC- or LC-MS. Nabumetone is a non-steroidal anti-inflammatory drug (NSAID) and a prodrug form of 6-methoxy naphthalene acetic acid .1 Nabumetone (5-45 mg/kg) reduces carrageenan-induced edema in rats, as well as UV-induced erythema in guinea pigs (ED50 = 11 mg/kg).2 It reduces phenyl-p-quinone-induced writhing in mice (ED50 = 152 mg/kg). Nabumetone (50, 100, and 200 mg/kg) reduces endotoxin-induced pyresis in rabbits.1.Cryer, B., and Feldman, M.Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugsAm. J. Med.104(5)413-421(1998)
2.Boyle, E.A., Freeman, P.C., Mangan, F.R., et al.Nabumetone (BRL 14777, 4-[6-methoxy-2-naphthyl]-butan-2-one): a new anti-inflammatory agentJ. Pharm. Pharmacol.34(9)562-569(1982)
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