產品屬性：
產品名稱 | Mesembrine |
規格 | 1mg、5mg、10mg |
貨號 | EY-01Y17277 |
Cas No.: 24880-43-1
別名: N/A
化學名: N/A
分子式: C17H23NO3
分子量: 289.4
溶解度: Chloroform: 10 mg/ml,Ethanol: 10 mg/ml
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Mesembrine is an alkaloid that has been found in S. tortuosum and has serotonin (5-HT) reuptake inhibitory activity.1 It selectively binds to the 5-HT transporter (SERT; IC50 = 4.3 μg/ml) over a variety of receptors (IC50s = 148->750 μg/ml).2 Mesembrine inhibits the reuptake of 5-HT in vitro (Ki = 1.4 nM). It has analgesic effects in the hot plate test when administered at a dose of 20 mg/kg but does not induce a preference in the conditioned place preference test (CPP).2,31.Krstenansky, J.L.Mesembrine alkaloids: Review of their occurrence, chemistry, and pharmacologyJ. Ethnopharmacol.19510-19(2017)
2.Harvey, A.L., Young, L.C., Viljoen, A.M., et al.Pharmacological actions of the South African medicinal and functional food plant Sceletium tortuosum and its principal alkaloidsJ. Ethnopharmacol.137(3)1124-1129(2011)
3.Loria, M.J., Ali, Z., Abe, N., et al.Effects of Sceletium tortuosum in ratsJ. Ethnopharmacol.155(1)731-735(2014)
特別提醒公司產品僅供科研使用
