產品屬性：
產品名稱 | MF-438 |
規格 | 1mg、5mg |
貨號 | EY-01Y17332 |
Cas No.: 921605-87-0
別名: N/A
化學名: N/A
分子式: C19H18F3N5OS
分子量: 421.44
溶解度: DMSO: 62.5 mg/mL (148.30 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1[1].EC50: 2.3 nM (rSCD1)[1]MF-438 exhibits an ED50 between 1 and 3 mg/kg in a mouse model[1].[1]. Léger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502.
特別提醒公司產品僅供科研使用
