產品屬性:
產品名稱 | Miro1 Reducer |
規格 | 10mg、50mg |
貨號 | EY-01Y17322 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C20H16FN7O.HCl

分子量: 425.85
溶解度: DMSO|42.58|100|
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
Promotes proteasomal degradation of Miro1 (mitochondrial Rho GTPase 1). Reduces Miro1 levels in fibroblasts from Parkinson's disease (PD) patients (IC50 = 7.8 μM). Exhibits no significant effect on related outer mitochondrial membrane protein Mitofusin. Reduces stress-induced degeneration of dopaminergic neurons derived from PD patient iPSCs. Rescues age-dependent neuronal loss and prolongs lifespan in fly PD models.
特別提醒公司產品僅供科研使用