產品屬性:
產品名稱 | ML-180 |
規格 | 1mg、5mg、10mg、25mg |
貨號 | EY-01Y17391 |
Cas No.: 863588-32-3
別名: N/A
化學名: N/A
分子式: C20H25ClN4O2

分子量: 388.9
溶解度: DMSO: 10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述:
ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 μM) with maximum efficacy of 64% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC50 = 2.05 μM).
特別提醒公司產品僅供科研使用