產品屬性：
產品名稱 | N,N’-Diphenethylurea |
規格 | 5 mg、10 mg、25 mg、50 mg |
貨號 | EY-01Y17466 |
Cas No.: 5467-84-5
別名: N/A
化學名: N/A
分子式: C17H20N2O
分子量: 268.4
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml,Ethanol: 1 mg/ml
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
N,N’-Diphenethylurea is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities.1 It inhibits Streptomyces chitin synthase 1 (IC50 = 14 μg/ml) but not C. albicans chitin synthase 2 when used at concentrations up to 280 μg/ml. N,N’-Diphenethylurea is active against the fungus C. neoformans and the plant pathogenic fungus R. solani (MIC = 50 μg/ml for both).2 It enhances insulin-induced adipocyte differentiation in 3T3-L1 and C3H/10T1/2 cells when used at concentrations of 30 and 100 μM.31.Iwai, Y., Hirano, A., Awaya, J., et al.1,3-Diphenethylurea from Streptomyces sp. No. AM-2498J. Antibiot. (Tokyo)31(4)375-376(1978)
2.Kim, N.R., Hwang, E.I., Bong, S.K., et al.Isolation of Candida albicans chitin synthase 1 inhibitor from Steptomyces sp. A6705 and its characterizationJ. Microbiol. Biotechnol.15(4)895-898(2005)
3.Choi, S.-S., Cha, B.-Y., Kagami, I., et al.N,N’-diphenethylurea isolated from Okinawan ascidian Didemnum molle enhances adipocyte differentiation in 3T3-L1 cellsJ. Antibiot. (Tokyo)64(3)277-280(2011)
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