產品屬性：
產品名稱 | LC3-mHTT-IN-AN1 |
規格 | 10mM*1mL in DMSO、5mg、10mg、50mg、100mg |
貨號 | EY-01Y17652 |
Cas No.: 486443-73-6
別名: N/A
化學名: N/A
分子式: C15H9Br2NO3
分子量: 411.04
溶解度: DMSO: 125 mg/mL (304.11 mM); H2O: < 0.1 mg/mL (insoluble)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1].[1]. Li Z, et al. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds. Nature. 2019 Nov;575(7781):203-209.
特別提醒公司產品僅供科研使用
