產品屬性：
產品名稱 | N-3-oxo-tetradecanoyl-L-Homoserine lactone |
規格 | 1mg、5mg、10mg、25mg |
貨號 | EY-01Y17726 |
Cas No.: 177158-19-9
別名: 3-oxo-C14-HSL; N-3-oxo-myristoyl-L-Homoserine lactone
化學名: 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-tetradecanamide
分子式: C18H31NO4
分子量: 325.4
溶解度: DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by the synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-3-oxo-tetradecanoyl-L-homoserine lactone (3-oxo-C14-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria.[1] [2] [3] It appears later than shorter acyl chain AHLs in developing biofilms [4] and, like other long chain 3-oxo-AHLs, stimulates the production of putisolvin, [5] which in turn, inhibits biofilm formation.
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