產品屬性：
產品名稱 | N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine |
規格 | N2-Isobutyryl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxyguanosine 500 mg |
貨號 | EY-01Y17887 |
Cas No.: 68892-41-1
別名: N/A
化學名: N/A
分子式: C35H37N5O7
分子量: 639.7
溶解度: DMF: 15mg/mL,DMSO: 15mg/mL,Ethanol: 30mg/mL,Ethanol:PBS (pH 7.2) (1:3): 0.25mg/mL
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine is a building block that has been used in the synthesis of oligodeoxyribonucleotides.1,2,3 1.Wilk, A., Grajkowski, A., Phillips, L.R., et al.The 4-[N-Methyl-N-(2,2,2-trifluoroacetyl)amino]butyl group as an alternative to the 2-cyanoethyl group for phosphate protection in the synthesis of oligodeoxyribonucleotidesJ. Org. Chem.64(20)7515-7522(1999)
2.Grajkowski, A., Pedras-Vasconcelos, J., Wang, V., et al.Thermolytic CpG-containing DNA oligonucleotides as potential immunotherapeutic prodrugsNucleic Acids Res.33(11)3550-3560(2005)
3.Cie?lak, J., and Beaucage, S.L.Thermolytic properties of 3-(2-pyridyl)-1-propyl and 2-[N-methyl-N-(2-pyridyl)]aminoethyl phosphate/thiophosphate protecting groups in solid-phase synthesis of oligodeoxyribonucleotidesJ. Org. Chem.68(26)10123-10129(2003)
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