產品屬性：
產品名稱 | PDK4-IN-1 hydrochloride |
規格 | 10mM*1mL in DMSO、5mg、10mg、50mg、100mg |
貨號 | EY-01Y17951 |
Cas No.: 2310262-11-2
別名: N/A
化學名: N/A
分子式: C22H20ClN3O2
分子量: 393.87
溶解度: DMSO: 125 mg/mL (317.36 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 hydrochloride potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 hydrochloride has antidiabetic, anticancer and anti-allergic activity[1].[1]. Lee D, et al. Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases. J Med Chem. 2019 Jan 24;62(2):575-588.
特別提醒公司產品僅供科研使用
