產品屬性：
產品名稱 | L-Methionine-d3 |
規格 | 100 mg、500 mg、1 g |
貨號 | EY-01Y17925 |
Cas No.: 13010-53-2
別名: N/A
化學名: N/A
分子式: C5H8D3NO2S
分子量: 152.2
溶解度: DMF: insol,DMSO: insol,Ethanol: insol,PBS (pH 7.2): 10 mg/ml
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
L-Methionine-d3 is intended for use as an internal standard for the quantification of L-methionine by GC- or LC-MS. L-Methionine is an essential amino acid.1,2 It is catabolized by methionine adenosyltransferase 2A (MAT2A), yielding the universal methyl donor S-.2 L-methionine has roles in purine and pyrimidine synthesis, polyamine synthesis, and glutathione production, as well as in various metabolic diseases and aging. Dietary methionine restriction (MR) prevents accelerated aging in a mouse model of progeria and increases the lifespan of yeast, Drosophila, C. elegans, mice, and rats.1,2 MR also improves insulin sensitivity and reduces adiposity in mice, as well as inhibits the growth and proliferation of several cancer cell lines.1.Wanders, D., Hobson, K., and Ji, X.Methionine restriction and cancer biologyNutrients12(3)684(2020)
2.Sanderson, S.M., Gao, X., Dai, Z., et al.Methionine metabolism in health and cancer: A nexus of diet and precision medicineNat. Rev. Cancer19(11)625-637(2019)
特別提醒公司產品僅供科研使用
