產品屬性：
產品名稱 | Triparanol |
規格 | 500μg、1mg、5mg、10mg |
貨號 | EY-01Y17962 |
Cas No.: 78-41-1
別名: N/A
化學名: N/A
分子式: C27H32ClNO2
分子量: 438
溶解度: DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 0.125 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 μM), which is an enzyme involved in the biosynthesis of cholesterol. It has antitumor properties, such as decreasing proliferation and inducing apoptosis in many cancer cell lines and slowing tumor growth in a mouse xenograft model. It can also decrease Hedgehog pathway signaling in cancer cells. Formulations containing triparanol were discontinued in the 1960s due to serious adverse side effects, including rapid cataract development.
特別提醒公司產品僅供科研使用
