產(chǎn)品屬性：
產(chǎn)品名稱(chēng) | Parishin C |
規(guī)格 | 500μg、1mg、5mg、10mg |
貨號(hào) | EY-01Y19754 |
Cas No.: 174972-80-6
別名: N/A
化學(xué)名: N/A
分子式: C32H40O19
分子量: 728.7
溶解度: DMF: 20 mg/ml,DMSO: 25 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7.2): 10 mg/ml
儲(chǔ)存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Parishin C is a phenolic glycoside and a major component of G. elata. It prevents inhibition of NMDA receptor (NMDAR) currents induced by amyloid-β (1-42) (Aβ42) in rat hippocampal neurons when used at a concentration of 2 μM. In vivo, parishin C (20 mg/kg) prevents Aβ42-induced inhibition of long-term potentiation (LTP) in rats. Parishin is an agonist of the serotonin (5-HT) receptor subtype 5-HT1A (Ki = 1.54 nM; EC50 = 34 nM for [35S]GTPγS binding) that reverses phencyclidine-induced increases in immobility time in the forced swim test, phencyclidine-induced decreases in interaction time in the social interaction test, and phencyclidine-induced impairments in visual recognition of a novel object in mice.
特別提醒公司產(chǎn)品僅供科研使用
