產(chǎn)品屬性：
產(chǎn)品名稱 | Bacopaside X |
規(guī)格 | 1mg、5mg、10mg、25mg |
貨號 | EY-01Y20419 |
Cas No.: 94443-88-6
別名: N/A
化學(xué)名: N/A
分子式: C46H74O17
分子量: 899.1
溶解度: Soluble in DMSO
儲存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Bacopaside X is a triterpenoid saponin that has been found in B. monniera and has antifungal and anticancer activities.1,2,3 It inhibits the growth of the fungi C. albicans, C. neoformans, and A. fumigatus (MIC = 50 μg/ml for all).2 Bacopaside X decreases the proliferation of MDA-MB-231, SHG44, HCT8, A549, and PC3M cancer cell lines with IC50 values of 14.3, 15.9, 9.8, 9.7, and 10.1 μM, respectively.3 It reduces tumor growth by 84.13% in an S180 sarcoma mouse allograft model when administered at a dose of 50 μmol/kg.|1. Zhou, Y., Shen, Y.-H., Zhang, C., et al. Triterpene saponins from Bacopa monnieri and their antidepressant effects in two mice models. J. Nat. Prod. 70(4), 652-655 (2007).|2. Li, X.-C., ElSohly, H.N., Nimrod, A.C., et al. Antifungal jujubogenin saponins from Colubrina retusa. J. Nat. Prod. 62(5), 674-677 (1999).|3. Peng, L., Zhou, Y., Kong, D.Y., et al. Antitumor activities of dammarane triterpene saponins from Bacopa monniera. Phytother. Res. 24(6), 864-868 (2010).
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