產品屬性：
產品名稱 | N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine |
規格 | 100 μg、500 μg |
貨號 | EY-01Y20934 |
Cas No.: 30414-15-4
別名: N/A
化學名: N/A
分子式: C20H20N2O11
分子量: 464.4
溶解度:
儲存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine is a microbial metabolite and degradation product of the bacterial siderophore enterobactin that has been found in Streptomyces and has anticancer activity.1,2,3 It inhibits invasion of 26-L5 murine colon cancer cells in a Matrigel? assay with an IC50 value of 2.7 μM.11.Igarashi, Y., Iida, T., Fukuda, T., et al.Catechoserine, a new catecholate-type inhibitor of tumor cell invasion from Streptomyces spJ. Antibiot. (Tokyo)65(4)207-209(2012)
2.O'Brien, I.G., Cox, G.B., and Gibson, F.Enterochelin hydrolysis and iron metabolism in Escherichia coliBiochim. Biophys. Acta237(3)537-549(1971)
3.Raines, D.J., Moroz, O.V., Blagova, E.V., et al.Bacteria in an intense competition for iron: Key component of the Campylobacter jejuni iron uptake system scavenges enterobactin hydrolysis productProc. Nat. Acad. Sci. USA113(21)5850-5855(2016)
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