產品屬性：
產品名稱 | Sulochrin |
規(guī)格 | 1mg、5mg |
貨號 | EY-01Y21083 |
Cas No.: 519-57-3
別名: N/A
化學名: 2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxy-benzoic acid, methyl ester
分子式: C17H16O7
分子量: 332.3
溶解度: DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
儲存條件: Store at -20°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Sulochrin is a fungal metabolite produced by A. terreus and Penicillium that exhibits antiallergenic, anti-angiogenic, and antiviral activities. Sulochrin inhibits eosinophil degranulation. It prevents leukotriene C4 (LTC4) release, O2- production, and IL-8 production (IC50s = 0.03, 8.2, 9.6, and 8.7 μM, respectively) and inhibits migration of human and guinea pig eosinophils (IC50 = 0.2-0.4 μM). Sulochrin inhibits VEGF-induced capillary tube formation of human umbilical vein endothelial cells (HUVEC) in vitro (70% inhibition at 10 mg/ml). It also inhibits hepatitis C viral infection (IC50 = 24.4 μM) in vitro.
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