產品屬性：
產品名稱 | Artemisinine |
規格 | 10mM (in 1mL DMSO)、20mg |
貨號 | EY-01Y21317 |
Cas No.: 63968-64-9
別名: Arteannuin
化學名: (5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(12H)-one
分子式: C15H22O5
分子量: 282.33
溶解度: ≥ 13.7mg/mL in DMSO
儲存條件: Store at 2-8°C
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Artemisinin (Qinghaosu), a sesquiterpene lactone,is an anti-malarial drug isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2].Artemisinin (Qinghaosu) (25 or 50 μM; 24 hours) concentration-dependently suppresses Aβ25-35 induced cytotoxicity in PC12 cells[1]. Artemisinin (1-100?μM; 24? hours) selectively inhibits cancer cell growth in a dose-dependent manner with IC50 values of 31.30?±?0.73?μM in UMRC-2 cells and 23.97?±?0.92 CAKI-2 cells[2]. Artemisinin (25, 50?μM; 24?hours) suppresses the phosphorylation of AKT in UMRC-2 and CAKI-2 cells in a dose-dependent manner[2].Artemisinin (gavage; 20?mg/kg/day; for two weeks) suppresses UMRC-2 xenograft tumor growth[2].
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